Neuroscience News – 21 May 26
Broken Sleep Rhythms: The Glymphatic Link to Dementia - Neuroscience News
A new study links stress, depression, and aging to dementia via the disruption of glymphatic brain cleaning cycles during sleep.
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研究认为，睡眠是一种高度有序的液体传输状态。当睡眠的同步节奏被打乱时，大脑的glymphatic系统就不能有效地排出有毒的淀粉样β蛋白和tau蛋白，从而为认知能力下降铺平道路。
Medical Xpress – 21 May 26
The brain's night shift: How sleep, waste clearance and dementia may be linked
Why are conditions such as chronic stress, depression, cardiovascular disease, fragmented sleep, and aging all associated with a higher risk of dementia? In a new review piece in Science, University of Rochester Medicine neuroscientist Maiken...
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文章的重点是神经调节剂–去甲肾上腺素、血清素、多巴胺和乙酰胆碱等大脑化学物质，它们能在清醒时调节情绪、注意力、学习和行为。
在非快速眼动睡眠期间，这些系统的表现有所不同，它们会同步产生缓慢、重复的振荡，大约每分钟一次。这些节律与大脑活动、心率、呼吸、血管运动和脑脊液流动的变化有关。
"几十年来，我们主要从记忆和恢复的角度来看待睡眠，"Nedergaard 说。"现在出现的观点是，睡眠也是一种高度有序的液体传输状态，有助于维持大脑健康。
News-Medical – 13 May 26
Disrupted circadian rhythms may accelerate dementia-related brain inflammation
Alzheimer's disease and other dementias impact approximately 55 million people worldwide, including 7.2 million cases in the United States alone.
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